Combinatorial regulation of gene expression suggests

Combinatorial regulation of gene expression suggests that DNA sequences bound by particular transcription factors might be mixed and matched in different combinations to provide different specificities for regulating downstream genes. Using three different sequence elements, how many combinations of 12, 2 or 3 elements can be envisaged? (Assume that their order of appearance on the DNA with respect to the promoter is also important).

 

 

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