Dentinogenesis imperfecta is tooth disorder production

Dentinogenesis imperfecta is a tooth disorder involving the production of dentin sialophosphoprotein, a bone-like component of the protective miIDle layer of teeth. The trait is inherited asan autosomal dominant. The mutant gene, located on chromosome 4,occurs in about 1 in 6000-8000 people. Assume that a man with dentinogenesis imperfecta, whose father had the disease, but whose mother had normal teeth, married a woman with normal teeth. They have six children. What is the probability that their first childwill be a male with dentinogenesis imperfecta? What is theprobability that 3 of the 6 children will have the trait?

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