Discuss implications on metabolism and metabolites

During strenuous exercise, the demand for ATP in skeletal muscleis greatly increased. In rabbits, most ATP is made by lactic acidfermentation. ATP is made at the substrate level phosphorylations,using phosphoglycerate kinase and pyruvate kinase. What wouldhappen during strenuous activity in rabbit skeletal muscle, if amutant form of lactate dehydrogenase with a low Vmax was present? Please discuss implications on metabolism and metabolites.

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