Identify the main chemical functionalities present in propofol and what possible impact they could have in the blood plasma pH
DIPRIVAN Injectable Emulsion is available in ready to use 20 mL infusion vials, 50 mL infusion vials, and 100 mL infusion vials containing 10mg/mL of propofol
Although dose must be adjusted according to the results of suitable lab tests, the following dose schedules may be used as guidelines:
<55 years: 2-2.5 mg/kg until onnset
>55 years: 1-1.5 mg/kg until onset
<55 years old: 0.1-0.2 mg/kg/min IV >55 years old: 0.05-0.1 mg/kg/min IV
The hospital has infusion equipment capable of control up to 0.01 mL. If a patient 45 years old and 195 pounds is treated with Diprivan , evaluate the following:
A) What is the IUPAC name for propofol?
B) Identify the main chemical functionalities present in propofol and what possible impact they could have in the blood plasma pH
C) Based on the content of this course, what is the expected solubility of propofol in water?
D) Why Diprivan is an emulsion?
E) Research/Investigate and briefly describe the main mechanism of action of propofol.
F) When used as recommended calculate the following:
If the induction occurs in approximately 30 seconds what is the flow required to administer the recommended dose?
If the procedure last for 2 hours, what is the maintenance flow required for the patient
At the end of the procedure how my mg of propofol were used?
How many mL of Diprivan were injected during the whole procedure?