From Gut to the Brain-Addressing Alzheimer’s Disease Probiotics: The use and effectiveness of Probiotics in the diminishing symptoms of Alzheimer’s disease. The purpose of the study is to provide nurses with current evidence-based knowledge as it relates to the use and effectiveness of probiotics in diminishing symptoms associated with Alzheimer’s Disease. Objectives: 1. Describe Alzheimer’s Disease per DSM5. a) Define Alzheimer’s Disease as outlined in the Diagnostic Statistical Manuel of Mental Disorders-5 (DSM-5). b) Explain signs and Symptoms of the AD. c) How it impacts the nation, population and health care system. d) List of treatment options/modalities for the client with AD 2. Summarize current knowledge as it relates probiotics. a) Define probiotics. b) Discuss the history of probiotics. c) Identify what kind of microorganisms probiotics are. d) Highlight the usefulness of probiotics. e) Outline the Safety and Side Effects of Probiotics. 3. Illustrate the relationship of Probiotics and Alzheimer’s Disease. o Pathophysiology of probiotics and the inflammatory process. o Role of Inflammatory process in AD development. o Cost Comparison of probiotics and conventional AD treatment. o Side Effect Comparison of probiotics and conventional AD treatment. 4. Examine two Evidence Based Research articles relating to probiotics and AD. a) Effect of Probiotic Supplementation on Cognitive Function and Metabolic Status in Alzheimer’s Disease: A Randomized, Double-Blind and Controlled Trial. (2016) Link: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5105117/ • Background • Objectives • Method • Population • Results b) Probiotic Supplementation in Patients with Alzheimer’s Dementia – An Explorative Intervention Study. (2018) Link: https://www.ncbi.nlm.nih.gov/pubmed/30101706 • Background • Objectives • Method • Population • Results 5 Integrate current EBR into Nursing Process as it relates to Probiotics and AD. a) Assessment b) Diagnosis c) Planning/Outcome d) Implementation e) Evaluation
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