They started with a stain of mouse in which the heavy chain and light chain loci had been `knocked-out” (made non-functional). They then introduced into embryos from these mice genes for heavy and light chains from humans; transgenic mice were then grown from these embryos. When exposed to antigens, these mice produce human antibodies against the antigens. A. Why was it necessary to start with Ig knock-out mice? B. The antibodies produced from the transgenic mice are `human” antibodies; how do these differ from the antibodies to the same antigen from normal mice? C. Would the transgenic mice recognize antigens as `foreign” differently than normal mice?
https://essaysprompt.com/wp-content/uploads/2020/10/19-2.png 0 0 https://essaysprompt.com/wp-content/uploads/2020/10/19-2.png 2022-12-20 22:48:032022-12-20 22:48:03They started with a stain of mouse in which the heavy chain and light chain loci
EssaysPrompt papers are NOT intended to be forwarded as finalized work as it is only strictly meant to be used for research and study purposes. EssaysPrompt does not endorse or condone any type of plagiarism.