What is DNAs function?

. How does the sequence of amino acids in a protein influence the way it folds? (1/2 pts)
2. A mutation in a gene results in a protein with a distorted three-dimensional structure. What is the likely effect of that mutation on the cell, and why? (1/2 pts)
3. Antithrombin deficiency results when a person inherits two defective alleles of the antithrombin gene. What do you think would happen if a person had one defective allele and the other allele was functional? (1/2 pts)
4. What is gene expression? How is it accomplished? (1/2 pts)
5. What is DNA’s function? (1/2 pts)
6. If there was a mutation in the regulatory sequence of a gene, what types of issues might arise? (1/2 pts)
7. Match the following items with the correct descriptions. (Each term may be used more than once.) (1/2 pts)
A. DNA B. All types of RNA C. tRNA D. mRNA
a. ______is a double helix b. _____ is a template for RNA c. _____ contains uracil d. _____ contains thymine e. _____ is the “recipe” for proteins f. _____ passes on genetic information to next generation g. _____ contains anticodons h. _____ never exits the nucleus i. _____ can carry amino acids j. _____ contains codons k. _____ can exit the nucleus
8. Put the following terms in the order they would be needed when a gene is expressed: amino acid, DNA, mRNA, protein, ribosome, transcription, tRNA (1/2 pts)
9. How is transcription different from translation with respect to 1) location, 2) template, and 3) end-product? (1/2 pts)
10. Of the molecules DNA, transfer RNA (tRNA), messenger RNA (mRNA), and amino acids, which are involved in transcription and which in translation? (1/2 pts)
11. Explain how RNA nucleotides match up with DNA nucleotides when RNA is made. (1/2 pts)
12. Put the following steps of transcription in order. (Not every step will be used.) (1/2 pts)
a. DNA unwinds b. DNA leaves the nucleus c. RNA polymerase binds to regulatory sequence d. mRNA leaves the nucleus e. DNA polymerase adds new nucleotides to the RNA f. DNA primer added g. RNA polymerase adds new nucleotides to the RNA
13. Compare anticodons and codons. (1/2 pts)
14. If a codon that normally codes for an amino acid is changed to a stop codon, how would that change alter the protein? (1/2 pts)
15. Describe how the change of a single nucleotide in the DNA sequence can have an effect on protein function. (1/2 pts)

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