How will the molecular pathway of hormone-receptor

A scientist is studying the function of a type of nuclear steroid receptor protein in mouse cells. She introduces various mutations into the gene encoding the receptor protein and transfers the genes into mice. If mutations are introduced that (a) eliminate the nuclear import signal in the receptor protein or (b) alter the receptor protein surface so that the receptor can no longer interact with Hsp70 protein, how will the molecular pathway of hormone-receptor interaction be altered?

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