Hscs for the treatment of heart attack

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Question: You have overexpressed p16INK4a in ESCs and you detect increased phosphorylation of RB. The cell cycle in those cells is inhibited with cells accumulating in S-phase. Is this possible?

Question: The fist clinical trial that assess stem cells in transplantation setting is using HSCs for the treatment of heart attack. Why are HSCs used and not cardiac stem cells?

 

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